Do the major MS drugs (the CRABs) really work?

Apparently not, according to this summary by Ashton Embry based on the large, long-term studies done in the United Kingdom and elsewhere: http://www.direct-ms.org/magazines/Embry%20MS%20Drugs%20Don%27t%20Work%2007%2010.pdf.  Certainly they don't seem to make any difference (statistically) in the progression of the disease.  Pretty damning, I would say.